gClinBiomarker is an R package that contains functions to perform baseline and longitutinal biomarker analyses. This version is wei's private version that fixes bugs and introduces features of critical needs.

Use the command vignette(package = 'gClinBiomarker') to view a list of avaialble vignettes for the gClinBiomarker package. Then use the command vignette(<vignett_name>) to view the relevant documentation.

• 2-arm study: predictive and prognostic biomarker analysis
• 1-arm study: prognostic biomarker analysis

Is your biomarker population your full patient population? Take a look at these functions:

SummaryVars(), CompareKM(), PlotRspBar()

Is your biomarker response a dynamic range? Does it have a skewed distribution? Is it correlated with clinical variables?

PlotProperty(), PlotTabForestMulti()

Is your biomarker response associated with a clinical outcome? Is it prognostic or predictive? Is there an optimal biomarker cutoff with a consistent trend?

PlotTabForestBiomarker(), PlotSTEPP()

Estimate the clinical benefit within a biomarker subgroup.

PlotKM(), PlotLong(), PlotRspBar(), CoxTab(), LogRankTab()