For more information, see http://ok100.github.io/lyvi/
You can install the python dependencies by issuing:
$ sudo pip install -r pip_requirements.txt --use-mirrorsThis will also be done for you when issuing the setup.py script.
There are other dependencies that need to be installed separately though:
libglyr(https://github.com/sahib/glyr)
For MPRIS support these dependencies are needed:
python-dbuspython-gobject
Chances are that all these are available by your package manager.