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Exploratory work on free energy calculations with GROMACS using "separated topologies" approach (Rocklin et al., 2013).

Python 28 9 Updated Dec 4, 2024

Lab website

SCSS 4 1 Updated Apr 10, 2025

Protein-Ligand Benchmark Dataset for Free Energy Calculations

Python 204 17 Updated Jul 29, 2024

OpenMM testbed for constant-pH methodologies.

Python 23 13 Updated Sep 20, 2021
TeX 1 Updated Dec 2, 2017

Tool collection to integrate and mix OpenEye and OpenMM

Python 14 1 Updated Jul 17, 2023

Chemical perception tree automated exploration tool.

Python 19 8 Updated Aug 14, 2018

Tools for open forcefield development

Python 8 6 Updated Aug 30, 2018

Datasets for open forcefield parameterization and development

Jupyter Notebook 11 7 Updated Sep 22, 2019

For discussing and aggregating data for force field development

Python 15 8 Updated Oct 19, 2016

A stripped-down set of just antechamber, sqm, and tleap.

C 33 19 Updated Sep 20, 2021

An open, extensible Python framework for GPU-accelerated alchemical free energy calculations.

Python 187 72 Updated Jul 6, 2023