diff --git a/nix/overlay.nix b/nix/overlay.nix
index 0ca1e1f163f..fd234a1fd0a 100644
--- a/nix/overlay.nix
+++ b/nix/overlay.nix
@@ -3,7 +3,11 @@ let
 in
 self: super:
 {
-  gpgme = (static super.gpgme);
+  gpgme = (static super.gpgme).overrideAttrs (x: {
+    # Drop the --enable-fixed-path:
+    # https://github.com/nixos/nixpkgs/blob/9a79bc99/pkgs/development/libraries/gpgme/default.nix#L94
+    configureFlags = self.lib.lists.remove "--enable-fixed-path=${self.gnupg}/bin" x.configureFlags;
+  });
   libassuan = (static super.libassuan);
   libgpg-error = (static super.libgpg-error);
   libseccomp = (static super.libseccomp);