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Python 60 24 Updated Oct 10, 2025

A fully open source biomolecular structure prediction model based on AlphaFold3

Python 450 44 Updated Nov 21, 2025

"AI-Trader: Can AI Beat the Market?" Live Trading Bench: https://ai4trade.ai

Python 9,708 1,525 Updated Nov 26, 2025
Jupyter Notebook 679 115 Updated Nov 27, 2025

Sidechain conditioning and modeling for full-atom protein sequence design

Python 127 22 Updated Nov 11, 2025

BindCraft modified to make PyRosetta use and installation optional: no license needed

Python 100 19 Updated Sep 20, 2025

Inference code for RFdiffusion2

Python 340 48 Updated Nov 11, 2025
Jupyter Notebook 15 2 Updated Nov 11, 2025

Potts model-based protein sequence design

Python 64 10 Updated Nov 13, 2025

A snakemake-based workflow for FEP and MM(PB/GB)SA calculations with GROMACS

Python 120 16 Updated Nov 19, 2025

Official repository for the ProteinDJ protein design pipeline

Python 71 12 Updated Nov 27, 2025

Codebase for Germinal, a broadly enabling generative pipeline for efficient generation of epitope-targeted de novo antibodies.

Python 162 24 Updated Nov 27, 2025

Code for running RFdiffusion

Python 2,600 544 Updated Nov 20, 2025

Application to assign secondary structure to proteins

C++ 226 28 Updated Nov 27, 2025

SpatialPPIv2: Enhancing protein–protein interaction prediction through graph neural networks with protein language models.

Python 21 2 Updated Aug 8, 2025

Scoring function for interprotein interactions in AlphaFold2 and AlphaFold3

Python 159 20 Updated Apr 6, 2025

List of papers about Proteins Design using Deep Learning

1,832 214 Updated Nov 29, 2025

Inference code for scalable emulation of protein equilibrium ensembles with generative deep learning

Python 697 113 Updated Nov 26, 2025

Foldseek enables fast and sensitive comparisons of large structure sets.

C 1,109 138 Updated Nov 21, 2025
Python 225 40 Updated Aug 12, 2025

A Unified Evaluation Suite for Protein Design

Python 104 8 Updated Nov 28, 2025

Multi-class signal peptide prediction and structure decoding model.

Python 97 17 Updated Feb 4, 2025

Improved antibody structure-based design using inverse folding

Python 144 26 Updated Aug 21, 2025

DockQ is a single continuous quality measure for Protein, Nucleic Acids and Small Molecule Docking Models

Python 344 71 Updated Nov 7, 2025

Graph transformer for estimating protein model accuracy

C 5 1 Updated Aug 22, 2025

Extension of ThermoMPNN for double mutant predictions

Python 49 15 Updated Oct 8, 2025

Protein-Ligand Interaction Profiler - Analyze and visualize non-covalent protein-ligand interactions in PDB files according to 📝 Schake, Bolz, et al. (2025), https://doi.org/10.1093/nar/gkaf361

Python 610 131 Updated Oct 30, 2025
Python 381 114 Updated Oct 31, 2025

Official Repository for the Uni-Mol Series Methods

Python 990 155 Updated May 29, 2025
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