Molecular Devices

In this Labcompare Q&A, Aaron Risinger of Molecular Devices shares why organoids are redefining how we approach complex biology. Here are six key benefits covered: 1. Human-relevant biology – Organoids recreate tissue architecture and cell-cell interactions that 2D cultures cannot. 2. Ethical innovation – They reduce dependence on animal models while increasing translational accuracy. 3. Quantitative monitoring – High-content imaging provides rich data on growth, morphology, and drug response. 4. Scalability through automation – Manual workflows limit throughput; automation and robotics remove bottlenecks. 5. AI-driven decision-making – Machine learning interprets imaging data to optimize when to feed, passage, or add growth factors during cell culture. 6. The move toward precision medicine – Patient-derived tumoroids enable drug testing tailored to individual biology. Aaron also points to how solutions like the CellXpress .ai Automated Cell Culture System are helping labs automate long-term culture and care of organoids—enabling reproducible, large-scale studies that were once incredibly challenging to perform manually. His perspective highlights the convergence of organoids, automation, and AI as a turning point for discovery and translational science. Read the full article here: https://hubs.la/Q03JpYw_0. #PrecisionMedicine #3DBiology #DrugDiscovery #LabAutomation #Organoids #DanaherNews

What makes modeling neurodegenerative diseases so challenging? As Dr. Felix Spira explains in his recent Technology Networks Q&A, it comes down to the lack of physiologically relevant model systems: https://hubs.la/Q03KWh0f0. Traditional animal and 2D cell models simply don’t capture the complexity of the human brain, nor do they provide an accurate model for studying the development of conditions like Alzheimer’s and Parkinson’s. Felix draws on his expertise in 3D biology, microscopy, and automation to show how brain organoids are transforming neuroscience. He also highlights how automation is addressing the “storm of challenges” researchers face—manual bottlenecks, inconsistent quality, and lack of standardization. And with innovations like the CellXpress .ai Automated Cell Culture System, scientists now have access to the reproducible models and scalable technology required to push neurodegenerative disease research forward. Read the full article featuring Felix’s insights: https://hubs.la/Q03KWh0f0. #BrainOrganoids #Neurodegeneration #Automation #LifeSciences #DanaherNews #FutureOfCellCulture

Curious how researchers are scaling 3D cell culture without sacrificing reproducibility? This free webinar will explore how automation is helping labs: – Reduce hands-on time – Improve consistency across experiments – Make smarter, real-time decisions with AI-powered insights Whether you're working with organoids, spheroids, or tumoroids—or just starting to explore 3D models—you’ll walk away with practical strategies to streamline your workflow and accelerate discovery. Date: Tuesday, September 30, 2025 Time: 10 AM PDT | 1 PM EDT | 7 PM CEST Register here: https://hubs.la/Q03J7f0F0 #Organoids #Spheroids #LabAutomation #FutureOfCellCulture #PrecisionMedicine

Understanding not just 𝘸𝘩𝘪𝘤𝘩 genes are active, but 𝘸𝘩𝘦𝘳𝘦 they’re active inside cells is key to unlocking deeper insights into disease and discovery. In our latest application note, we demonstrate how the ImageXpress HCS .ai High-Content Screening System and AI-powered IN Carta Software enable: ✔️ Reliable single-molecule RNA detection—even for faint signals ✔️ Accurate transcript-to-cell assignment with advanced AI segmentation ✔️ Full-well imaging for comprehensive spatial transcriptomics studies The result? A powerful way to connect gene expression with cell morphology—revealing insights into cancer, neurological disorders, inflammation, and beyond. Download the application note to explore how spatial transcriptomics is advancing complex biological research. 🔗 https://bit.ly/3Kfpt8t #HighContentImaging #SpatialTranscriptomics #DrugDiscovery #DeeperInsightsForEveryLab

From India to San Jose, Boston to Winnersh, our associates came together for our annual Culture Day—a celebration of the people, traditions, and experiences that make our global community so special. This year’s events brought the world into our offices, with associate-hosted booths showcasing various cultures. From flavorful dishes to lively games and performances—including a Bollywood dance session that had everyone smiling—each experience highlighted the richness and creativity of our teams. Culture Day is more than a single event; it’s a reminder of how powerful shared experiences can be in building connection, understanding, and belonging. Whether stamping “passports” at booths, tasting something new, or simply enjoying conversations, our associates made the day unforgettable.

Will you be at the Festival of Biologics? Join us along with other Danaher Life Science companies at booth 502 to learn about end-to-end solutions that accelerate drug discovery and development. Our experts are ready to partner with you and discuss how, together, we can accelerate biologics discovery through automation, microbiome research, and therapeutic development. Click here to learn more: https://hubs.la/Q03J8r-V0 See you there!

Neuroscience is evolving—and so are the models we rely on. Animal models have long been central to brain research, but they often fall short of replicating human biology. iPSC-derived brain organoids offer a more accurate, ethical, and scalable alternative—and now, their development can be automated. In this new blog post, Dr. Sandra Grund-Gröschke explores how researchers are using automation to streamline brain organoid culture and unlock deeper insights into brain function and disease. It’s a look at where neuroscience is headed and how labs are getting there faster. Read the full story: https://hubs.la/Q03JSyKh0 #Neuroscience #Organoids #iPSC #BrainResearch #LabInnovation #BeyondAnimalModels #FutureOfCellCulture

Your high-content imager is only as powerful as the software behind it. That's where our IN Carta Image Analysis Software comes in—bringing AI-driven intelligence to every dataset. In this NEW on-demand webinar, Dr. Misha Bashkurov demonstrates how IN Carta helps you: ☑️ Automate complex analyses to accelerate workflows and reduce manual variability ☑️ Improve detection accuracy using the SINAP module's custom deep learning models tailored to your experiments ☑️ Characterize phenotypic diversity with the Phenoglyphs module for robust multi-parametric data analysis ☑️ Turn large datasets into actionable results—making it easier to uncover new biology and advance research decisions Whether you’re working at the bench or guiding research strategy, this webinar showcases how AI-driven analysis can unlock more value from every dataset. 🔗 https://bit.ly/3KeWkdv #HighContentImaging #AI #MachineLearning #DrugDiscovery #PhenotypicProfiling #3DBiology

In this Labcompare interview, Aaron Risinger details how intelligent automation reduces the unpredictability that has long hampered organoid cell culture: https://hubs.ly/Q03JpMTF0. By combining robotics, high-content imaging, and machine learning, labs can monitor organoid morphology and health in real time—ultimately enabling more reproducible, scalable studies. His insights underscore a shift away from intuition-based decisions and support the move toward standardized workflows that unlock the full potential of organoids in modeling disease. #AIinScience #OrganoidReproducibility #Automation #DanaherNews

⏰ The countdown is on — it is the final day at Ilmac Basel🇨🇭 Doors are closing soon, so make sure you stop by Booth C120. Our team is eager to meet you and show the innovations we are presenting: the SpectraMax® iD5e, ImageXpress® HCS .ai, and QPix® FLEX. Do not miss your last chance to connect with us before the show wraps up. 📍 Booth C120 – ILMAC 2025, Basel Discover the new ImageXpress HCS .ai ➡️ bit.ly/ImageXpressHCSai